Is the Tamron 16-300mm f/3.5-6.3 Di II VC PZD Macro Lens sharp? This page visually answers that question. Shown above are 100% crops from a lab-captured 35mm f/5.0 test image. Observe the contrast and resolution of these results.
Is the Tamron 16-300mm f/3.5-6.3 Di II VC PZD Macro Lens set to 35mm f/5.0 sharper than the Nikon 18-55mm f/3.5-5.6G II AF-S DX Nikkor Lens set to 45mm f/5.3? The image quality comparison above also answers that question. Switch between the results to see the sharpness differences between these lenses.