Is the Canon RF 100-500mm F4.5-7.1 L IS USM Lens sharp? This page visually answers that question. Shown above are 100% crops from a lab-captured 700mm f/10.0 test image. Observe the contrast and resolution of these results.
Is the Canon RF 100-500mm F4.5-7.1 L IS USM Lens set to 700mm f/10.0 sharper than the Canon RF 800mm F11 IS STM Lens set to 1600mm f/22.0? The image quality comparison above also answers that question. Switch between the results to see the sharpness differences between these lenses.